Bacteriophage therapy as an alternative treatment for human infections. A comprehensive review

Antimicrobial resistance (AMR) is a global, increasing and major health problem. The World Health Organization, on its first global report on antibiotic resistance, has highlighted the danger of an upcoming post-antibiotic era, where simple infections could once again be lethal [1]. The Centre for Disease Control (CDC) estimates that at least 23000 deaths per year in the USA are a result of infection by resistant bacteria [2], while in Europe growing levels of antibiotic resistance are being reported, especially in countries with existing high levels of multi-drug resistance, resulting in the limitation of therapeutic options [3].On the other side, pharmaceutical companies are showing a decline in their interest of developing and producing novel antibacterial agents, mostly because the antibacterial market is being less profitable than others [4].
Source: International Journal of Antimicrobial Agents - Category: Drugs & Pharmacology Authors: Tags: Review Source Type: research