Evaluation of the vitros hiv combo 4th generation test for the identification of hiv infections

Antibody detection against Human Immunodeficiency Virus (HIV) is a commonly-used method for screening HIV infection. Over time, with the improvement of immunological techniques, several generations of tests for detection of anti-HIV antibodies have been developed. The first generation tests, which used an HIV lysate as the source of antigens for the test preparation, had some specificity problems that were minimized in second generation tests which used recombinant antigens (eg in Escherichia coli).

Source: Journal of Clinical Virology - September 17, 2018 Category: Virology Authors: Massimo De Paschale, Maria Teresa Manco, Annalisa Cianflone, Luisa Belvisi, Debora Cagnin, Teresa Cerulli, Alessia Paganini, Carlo Agrappi, Paola Mirri, Pierangelo Clerici Source Type: research