Severity-dependent and -independent brain regions of major depressive disorder: a long-term longitudinal near-infrared spectroscopy study

To establish neuroimaging biomarkers for major depressive disorder (MDD), investigations into longitudinal relationships with symptomatology are important. Previous studies using structural or functional MRI (fMRI) demonstrated the cross-sectional association between depression severity and neuroimaging indicators (Hall et  al., 2014; Zhang et al., 2016). However, no studies on neuroimaging in MDD have followed clinical outcomes and brain functions over a longer period of time (1-2 years).

Source: Journal of Affective Disorders - September 17, 2018 Category: Neurology Authors: Yoshihiro Satomura, Eisuke Sakakibara, Ryu Takizawa, Shinsuke Koike, Yukika Nishimura, Hanako Sakurada, Mika Yamagishi, Chie Shimojo, Shingo Kawasaki, Naohiro Okada, Jun Matsuoka, Akihide Kinoshita, Seiichiro Jinde, Shinsuke Kondo, Kiyoto Kasai Tags: Research paper Source Type: research