Pretreatment brain connectivity during positive emotion upregulation predicts decreased anhedonia following Behavioral Activation Therapy for Depression

Behavioral Activation Therapy for Depression (BATD) is an intervention designed to ameliorate core symptoms of major depressive disorder (MDD) by promoting systematic engagement in valued activities and reductions in avoidance behaviors. The overarching goal of BATD is to increase contact with potential sources of positive reinforcement (Dimidjian  et al., 2011). In line with the emerging science of neuroprediction to better match MDD patients to existing treatments (e.g., Langenecker et al., 2018; Pizzagalli et al., 2018), our recently completed open trial investigated neuroimaging predictors of BATD response (Walsh et al., 2017; Carl e t al., 2016; Crowther et al., 2015).

Source: Journal of Affective Disorders - September 17, 2018 Category: Neurology Authors: Erin C. Walsh, Tory A. Eisenlohr-Moul, Jared Minkel, Joshua Bizzell, Chris Petty, Andrew Crowther, Hannah Carl, Moria J. Smoski, Gabriel S. Dichter Source Type: research