Cardiovascular comorbidity increases the risk for renal failure during prophylactic lithium treatment

Lithium enjoys the strongest evidence among today ´s mood stabilisers for long-term relapse prevention of bipolar disorders and has been shown to reduce the risk of suicide. However, the benefits of lithium are restricted by its adverse side effects, the most serious being the progression of renal insufficiency to end-stage renal disease (ESRD) wi th need for renal replacement therapy (RRT, i.e. dialysis and renal transplantation).

Source: Journal of Affective Disorders - September 17, 2018 Category: Neurology Authors: Harald Aiff, Per-Ola Attman, Bernd Ramsauer, Staffan Sch ön, Jan Svedlund Tags: Research paper Source Type: research