One step ahead: miRNA-34 in colon cancer-future diagnostic and therapeutic tool?

Colorectal cancer (CRC) is the third most common cancer worldwide. The last global statistics were provided for 2012, with approximately 1.4 million new cases and 0.7 million deaths (Ferlay et al. 2013). In 2017 in the United States alone approximately 135,430 new cases and 50,260 deaths were reported, while in 2015 in China around 350,000 new cases and 190,000 deaths were noted (Chen et al. 2016; Siegel et al. 2017). The majority of cases occur in more developed regions, which points to the importance of environmental risk factors in colorectal carcinogenesis, such as improper dietary habits, insufficient physical activity, excessive body weight, smoking and alcohol consumption (Ferlay et al.
Source: Critical Reviews in Oncology Hematology - Category: Cancer & Oncology Authors: Source Type: research