Editorial Comment

In this retrospective analysis the authors explored the correlation between pretreatment prostate MRI suspicion scores and post-prostatectomy histological and genotypic risk stratification. The outcomes suggest an association between high risk preoperative MRI (PIRADS 5) and an increased genotype and expression based risk profile as quantified by up-regulation of the molecular pathways associated with tumor progression and castrate resistance. The novelty of the findings is in part captured in figure 4, which demonstrates increased pathway activation and an association with an increasing PIRADS score.
Source: The Journal of Urology - Category: Urology & Nephrology Authors: Tags: Adult Urology Source Type: research