Comprehensive analysis of published studies involving systemic treatment for chondrosarcoma of bone between 2000 and 2013

Conclusion Because chondrosarcoma of bone is an orphan disease it is difficult to conduct clinical trials. The meagre outcome data for locally advanced or metastatic patients indicate that new treatment options are needed. For the phase I trials it is difficult to draw conclusions because of the low numbers of chondrosarcoma patients enrolled, and at different dose levels. Some phase II trials show promising results which support further research. Retrospective studies are encouraged as they could add to the limited data available. Efforts to increase the number of studies for this orphan disease are urgently needed.
Source: Clinical Sarcoma Research - Category: Cancer & Oncology Source Type: research