Errors In Power-Law Estimations Of Inflow Rates For Intracranial Aneurysm CFD

Patient-specific inflow rates are rarely available for computational fluid dynamics (CFD) studies of intracranial aneurysms. Instead, inflow rates are often estimated from parent artery diameters via power laws, i.e. Q ∝Dn, reflecting adaptation of conduit arteries to demanded flow. The present study aimed to validate the accuracy of these power laws. Internal carotid artery (ICA) flow rates were measured from 25 ICA aneurysm patients via 2D phase contrast MRI. ICA diameters, derived from 3D segmentation of rota tional angiograms, were used to estimate inflow rates via power laws from the aneurysm CFD literature assuming the same inlet wall shear stress (WSS) (n=3), velocity (n=2) or flow rate (n=0) for all cases.

Source: Journal of Biomechanics - September 12, 2018 Category: Biomedical Science Authors: C. Chnafa, P. Bouillot, O. Brina, M. Najafi, B.M.A. Delattre, M.I. Vargas, V.M. Pereira, D.A. Steinman Source Type: research