Cortical biometals: Changed levels in suicide and with mood disorders

Genetic studies indicate common risk genes that contribute to an increased susceptibility to several psychiatric disorders (Consortium, 2013), suggesting there may be some common pathophysiological pathways affected across such disorders. Neuroimaging studies report mutual and differential changes in CNS structures in patients with the bipolar disorders and major depressive disorders (Konarski et al., 2008). Importantly, whilst both bipolar disorders and major depressive disorders are defined by the presence of depressive symptoms, bipolar disorders are ultimately defined by the presentation of manic or hypomanic episodes (American Psychiatric Association, 2013).
Source: Journal of Affective Disorders - Category: Neurology Authors: Tags: Research paper Source Type: research