Adding a statin may improve periodontal status

Statin drugs are widely used to reduce blood cholesterol levels in patients with hyperlipidemia and arteriosclerosis. They are also used preventively against coronary artery diseases, principally to lower low-density lipoprotein cholesterol. Statins also exert effects via pleiotropic mechanisms, which can have pharmacological effects such as antioxidant and anti-inflammatory properties, angiogenesis, improved endothelial function, and increased bone formation. Statins may also decrease interleukin (IL)-1 β and increase IL-10 levels in the gingival crevicular fluid of patients with periodontitis.
Source: Dental Abstracts - Category: Dentistry Tags: Inquiry Source Type: research