Radiotherapy in triple-negative breast cancer: current situation and upcoming strategies

Triple-negative breast cancer (TNBC) (estrogen receptor-negative, progesterone receptor-negative, and HER2-negative) is viewed as an aggressive subgroup of breast cancer. Treating patients with TNBC remains clinically challenging. It ’s now well established than radiation therapy is able to improve locoregional control in breast cancer patients both after breast conserving surgery or mastectomy, with positive impact in high-risk patients for long-term survival. Biologic characterization of breast tumor different subtypes, in p articular the heterogeneous subtype of TNBC could permit to adapt the treatment plan.

Source: Critical Reviews in Oncology Hematology - September 12, 2018 Category: Cancer & Oncology Authors: Ming Yuan He, Chlo é Rancoule, Amel Rehailia-Blanchard, Sophie Espenel, Jane-Chloé Trone, Emilie Bernichon, Elodie Guillaume, Alexis Vallard, Nicolas Magné Source Type: research