Cord blood concentrations of leptin, zinc- α2-glycoprotein, and adiponectin, and adiposity gain during the first 3 mo of life

Adipose tissue development is known to begin during intrauterine life. This tissue involves a variety of signaling molecules and mediators called cytokines that establish the link between adipose and other vital tissues such as the endothelium, heart, and placenta. These molecules participate in signaling of the inflammatory cascade, which is associated with the risk of developing chronic diseases later in life [1 –4]. These cytokines include leptin, zinc-α2-glycoprotein (ZAG), and adiponectin. Leptin has been recognized as a regulator of appetite in the hypothalamus [5].

Source: Nutrition - March 22, 2018 Category: Nutrition Authors: Ver ônica L.V. Euclydes, Natalia P. Castro, Lourdes R. Lima, Cyro Brito, Laisa Ribeiro, Fernanda Agapito Simões, Guaraci Requena, Liania Alves Luzia, Patricia Helen Rondó Tags: Applied nutritional investigation Source Type: research