Association of the FTO fat mass and obesity –associated gene rs9939609 polymorphism with rewarding value of food and eating behavior in Chilean children

Epidemiologic data suggest that some people are more susceptible than others to weight gain [1]. Data from monozygotic and dizygotic twins have shown that body mass index (BMI) is nearly as heritable as height [2], where it is estimated that 40% to 70% of the variance in obesity susceptibility can be attributed to genetic differences [3]. The fat mass and obesity –associated (FTO) gene remains the locus with the highest shared variance on BMI in adults and children, where the minor allele increases BMI by 0.39 kg/m2 and risk for obesity by 1.20-fold [3].
Source: Nutrition - Category: Nutrition Authors: Tags: Applied nutritional investigation Source Type: research