White matter – emotion processing activity relationships in youth offspring of bipolar parents

Bipolar Disorder (BD) is a debilitating psychiatric disorder characterized by recurrent, episodic disturbances in mood, sleep, behavior, perception, and cognition, rendering it a leading cause of disability, morbidity, and mortality worldwide(Mahon  et al., 2010). BD affects 1-3% of the adult population and has a heritability of 59-87%, placing first-degree relatives of individuals with BD at a 10-fold increased risk of the disorder versus relatives of unaffected controls(Merikangas et al., 2007; Phillips and Swartz, 2014; Singh and Chang, 2013; Smoller and Finn, 2003).

Source: Journal of Affective Disorders - September 10, 2018 Category: Neurology Authors: Heather E. Acuff, Amelia Versace, Michele A. Bertocci, Lindsay C. Hanford, Cecile D. Ladouceur, Anna Manelis, Kelly Monk, Lisa Bonar, Alicia McCaffrey, Benjamin I. Goldstein, Tina R. Goldstein, Dara Sakolsky, David Axelson, LAMS Consortium, Boris Birmaher Tags: Research paper Source Type: research