Pharmacokinetics and pharmacodynamics of propofol with or without 2% benzyl alcohol following a single induction dose administered intravenously in cats

Conclusions and clinical relevanceThe addition of 2% benzyl alcohol as a preservative minimally altered the pharmacokinetics and pharmacodynamics of propofol 1% emulsion when administered as a single IV bolus in this group of cats. These data support the cautious use of propofol with 2% benzyl alcohol for induction of anesthesia in healthy cats.

Source: Veterinary Anaesthesia and Analgesia - October 20, 2014 Category: Veterinary Research Authors: Gregg M Griffenhagen, Marlis L Rezende, Daniel L Gustafson, Ryan J Hansen, Paul J Lunghofer, Khursheed R Mama Tags: Research Paper Source Type: research