The potential mechanism of cholagogic effect about Gardenia Jasminoides Ellis (Zhizi)-mediated increase of bile acids urinary excretion in normal rats

ConclusionThe findings indicate that Zhi-zi reduces hepatic total BAs level by increasing urinary excretion rather than the biliary excretion of BAs, which, in turn ascribed to elevated protein expression of Mrp2 at apical membrane of renal tubular epithelial cells.
Source: Chinese Herbal Medicines - Category: Complementary Medicine Source Type: research