Molecular epidemiology of coxsackievirus A6 circulating in Hong Kong reveals common neurological manifestations and emergence of novel recombinant groups

Human enteroviruses are responsible for wide spectrum of diseases, ranging from febrile exanthema to meningitis and myocarditis. While enterovirus A71 (EV-A71) and coxsackievirus A16 (CV-A16) are the most common pathogens causing hand-foot-and-mouth disease (HFMD) in young children, infections caused by other enteroviruses are increasingly reported. CV-A6, belonging to enterovirus species A (EV-A) is a major pathogen of herpangina and an emerging cause of HFMD in Asia [1 –4]. CV-A6 infections with neurological involvement, such as acute flaccid paralysis and aseptic meningitis are also increasingly reported [5–8].

Source: Journal of Clinical Virology - September 8, 2018 Category: Virology Authors: Susanna K.P. Lau, Pyrear S.H. Zhao, Siddharth Sridhar, Cyril C.Y. Yip, Kam Leng Aw-Yong, Elaine Y.Y. Chow, Kelvin C.M. Cheung, Rex W.H. Hui, Ryan Y.H. Leung, Yuki S.K. Lai, Alan K.L. Wu, Kelvin K.W. To, Patrick C.Y. Woo, Kwok-Yung Yuen Source Type: research