Ginsenosides: The need to move forward from bench to clinical trials

Publication date: Available online 7 September 2018Source: Journal of Ginseng ResearchAuthor(s): Seung Eun Yu, Benjamin Mwesige, Young-Su Yi, Byong Chul YooAbstractPanax ginseng, known as Koran ginseng, one of the most commonly used traditional plants, has been demonstrated to show a wide range of pharmacological applications. Ginsenosides is the major active ingredients found in ginseng and is responsible for the biological and pharmacological activities, such as anti-oxidation, anti-inflammation, vasorelaxation, and anti-cancer actions. Existing studies have mostly focused on identifying and purifying single ginsenosides and investigating pharmacological activities and molecular mechanisms in cells and animal models. However, ginsenoside studies based on clinical trials have been very limited. Therefore, this review aimed to discuss the currently available clinical trials on ginsenosides and provide insights and future directions for developing ginsenosides as efficacious and safe drugs for human disease.
Source: Journal of Ginseng Research - Category: Complementary Medicine Source Type: research