Contribution of Murine Double Minute 2 Genotypes to Colorectal Cancer Risk in Taiwan

Conclusion: The genotypes of MDM2 SNP309 may allow forr early detection of and predictor for CRC risk, especially among smokers and non-alcohol drinkers, but not for prognosis. The combined effects of MDM2 SNP309 and other genes (such as matrix metalloproteinases) on CRC susceptibility and prognosis, should also be taken into consideration in the era of precision medicine.

Source: Cancer Genomics and Proteomics - September 7, 2018 Category: Cancer & Oncology Authors: YUEH, T.-C., HUNG, Y.-W., SHIH, T.-C., WU, C.-N., WANG, S.-C., LAI, Y.-L., HSU, S.-W., WU, M.-H., FU, C.-K., WANG, Y.-C., KE, T.-W., CHANG, W.-S., TSAI, C.-W., BAU, D.-T. Tags: Article Source Type: research