Comparative evaluation of Xpert MTB/RIF assay with multiplex polymerase chain reaction for the diagnosis of tuberculous meningitis

Rapid and specific diagnosis of tuberculous meningitis (TBM) is of paramount importance to decrease morbidity and mortality. Therefore, the present study was undertaken to compare the efficacy of Xpert MTB/RIF assay (GXpert) and multiplex PCR (MPCR) using three targets (IS6110, MPB64 and protein B) for diagnosing tuberculous meningitis.

Source: Tuberculosis - September 6, 2018 Category: Respiratory Medicine Authors: Kusum Sharma, Megha Sharma, Lokesh Chaudhary, Manish Modi, Manoj Goyal, Navneet Sharma, Aman Sharma, Anumiti Jain, Deba Prasad Dhibar, Kajal Jain, Niranjan Khandelwal, Pallab Ray, Vivel Lal, Max Salfinger Tags: Diagnostics Source Type: research