Towards Semantic-Driven High-Content Image Analysis. An Operational Instantiation for Mitosis Detection in Digital Histopathology

This study concerns a novel symbolic cognitive vision framework emerged from the Cognitive Microscopy (MICO1) initiative. MICO aims at supporting the evolution towards digital pathology, by studying cognitive clinical-compliant protocols involving routine virtual microscopy. We instantiate this paradigm in the case of mitotic count as a component of breast cancer grading in histopathology. The key concept of our approach is the role of the semantics as driver of the whole slide image analysis protocol.
Source: Computerized Medical Imaging and Graphics - Category: Radiology Authors: Source Type: research