Application of ultrasound accelerates the decalcification process of bone matrix without affecting histological and immunohistochemical analysis

ConclusionThe application of US decalcification significantly shortened the decalcification time in EDTA without causing histological artefacts.The translational potential of this articleThis article shows that the application of ultrasound in sample decalcification would shorten the duration that decalcification required. This would accelerate the sample processing for routine bone histology in both basic and clinical research and assessments for diagnostic purposes.
Source: Journal of Orthopaedic Translation - Category: Orthopaedics Source Type: research