BCAP links IL-1R to the PI3K-mTOR pathway and regulates pathogenic Th17 cell differentiation

This study establishes BCAP as a critical link between IL-1R and the metabolic status of activated T cells that ultimately regulates the differentiation of inflammatory Th17 cells.

Source: The Journal of Experimental Medicine - September 3, 2018 Category: Internal Medicine Authors: Deason, K., Troutman, T. D., Jain, A., Challa, D. K., Mandraju, R., Brewer, T., Ward, E. S., Pasare, C. Tags: Autoimmunity, Metabolism Articles Source Type: research