Relationship between latent and rebound viruses in a clinical trial of anti-HIV-1 antibody 3BNC117

In conclusion, viruses emerging during ATI in individuals treated with 3BNC117 are not the dominant species found in the circulating latent reservoir, but frequently appear to represent recombinants of latent viruses.

Source: The Journal of Experimental Medicine - September 3, 2018 Category: Internal Medicine Authors: Cohen, Y. Z., Lorenzi, J. C. C., Krassnig, L., Barton, J. P., Burke, L., Pai, J., Lu, C.-L., Mendoza, P., Oliveira, T. Y., Sleckman, C., Millard, K., Butler, A. L., Dizon, J. P., Belblidia, S. A., Witmer-Pack, M., Shimeliovich, I., Gulick, R. M., Seaman, Tags: Infectious Disease and Host Defense Articles Source Type: research