Microglial translational profiling reveals a convergent APOE pathway from aging, amyloid, and tau

This study has broad implications for microglial transcriptomic approaches and provides new insights into microglial pathways associated with different pathological aspects of aging and AD.

Source: The Journal of Experimental Medicine - September 3, 2018 Category: Internal Medicine Authors: Kang, S. S., Ebbert, M. T. W., Baker, K. E., Cook, C., Wang, X., Sens, J. P., Kocher, J.-P., Petrucelli, L., Fryer, J. D. Tags: Neuroinflammation, Innate Immunity and Inflammation, Neuroscience Brief Definitive Reports Source Type: research