The Value of Heterogeneity for Cost-Effectiveness Subgroup Analysis: Conceptual Framework and Application

This study presents the expected net benefits under current and perfect information when subgroups are defined based on the use and combination of 6 binary covariates. The results of the case study confirm the theoretical expectations. As more subgroups are considered, the marginal net benefit gains obtained under the current information show diminishing marginal returns, and the expected value of perfect information shows a decreasing trend. We present a suggested algorithm that synthesizes the results to guide policy.
Source: Medical Decision Making - Category: Health Management Authors: Tags: Original Articles Source Type: research