Re: Comparison of Pathological Stage in Patients Treated with and without Neoadjuvant Chemotherapy for High Risk Upper Tract Urothelial Carcinoma

Liao et  al report outcomes of patients with high risk upper tract urothelial carcinoma (UTUC) treated with or without neoadjuvant chemotherapy. The survival rate of patients with high risk UTUC is poor despite the fact that radical nephroureterectomy (RNU) has been the standard treatment for this conditio n. The authors suggest that patients treated with neoadjuvant chemotherapy before RNU had a reduction in pathological tumor stage and a decreased prevalence of pT2 or higher disease. Interestingly we noted that the prevalence of Tis was higher in patients who had undergone neoadjuvant chemotherapy t han those who had not.
Source: The Journal of Urology - Category: Urology & Nephrology Authors: Tags: Letter to the Editor/Errata Source Type: research