Protective Effects of Baicalin on Experimental Myocardial Infarction in Rats
This study aimed to investigate the protective effects of baicalin on
myocardial infarction in rats and explore the related mechanisms.Methods: Fifty Sprague Dawley rats were randomly divided into the control, model, and
low-, medium- and high-dose baicalin groups. The latter 3 groups were
intraperitoneally injected with baicalin, with a dose of 12.5, 25 and 50
mg/kg, respectively. Then, the myocardial infarction model was established.
The hemodynamic of rats was tested, the serum lactate dehydrogenase (LDH),
creatine kinase-MB (CK-MB), prostacyclin (PGI2) and thromboxane
A2 (TXA2) were determined, the myocardial
...
Source: Brazilian Journal of Cardiovascular Surgery - Category: Cardiology Source Type: research
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