Renal infiltration presenting as acute kidney injury in Hodgkin Lymphoma – a case report and review of the literature

Publication date: Available online 29 August 2018Source: Leukemia Research ReportsAuthor(s): Wellington Fernandes da Silva Junior, Laila Lopes de Farias Pinho, Cássio Lins Gil de Farias, Verônica Torres, Elerson Carlos Costalonga, George Coura Filho, Leonardo de Abreu Testagrossa, Vanderson Rocha, Valeria BuccheriAbstractRenal involvement in Hodgkin lymphoma (HL) is rare, although extralymphatic disease is usually found. Acute kidney injury is a recognized presentation of non-Hodgkin lymphoma, with bilateral kidney involvement, promptly requiring specific treatment. Regarding to HL, this manifestation is extremely rare and lacks pathologic description and management experiences. Herein, we describe a case of HL with atypical presentation as well as its management, current evaluation by PET-scan and histologic findings. This case report highlights clinical presentation and a successful experience on managing these cases. Moreover, it is important to drive biologic insights for understanding of kidney infiltration mechanism in HL.
Source: Leukemia Research Reports - Category: Hematology Source Type: research