Connecting clinical aspects to corticomotor excitability in restless legs syndrome: a TMS study

We assessed corticomotor excitability in the primary motor cortex (M1) of participants with moderate-to-severe restless legs syndrome (RLS) symptoms using transcranial magnetic stimulation (TMS) in relation to the clinical and sleep aspects of the disease. Thirty-five participants (20  F; mean age: 59.23 ± 1.66 years; range: 42–78 years) affected by primary RLS (off medications) and 31 age-matched controls (19 F; mean age: 57.90 ± 1.50 years; range: 43–79 years) underwent TMS following two nights of polysomnography (PSG).

Source: Sleep Medicine - May 30, 2018 Category: Sleep Medicine Authors: Rachel Marie E. Salas, Aadi Kalloo, Christopher J. Earley, Pablo Celnik, Tiana E. Cruz, Keyana Foster, Gabriela Cantarero, Richard P. Allen Tags: Original Article Source Type: research