The association between human papillomavirus 16, 18 DNA load and E6 protein expression in cervical intraepithelial neoplasia and cancer

Cervical cancer is the fourth most common cancer in women around the world, with an estimated 528,000 new cases and 266,000 deaths each year [1]. Infection with high-risk human papillomavirus (HPV) is now recognized as the cause of cervical cancer. The most common types detected in cervical cancer worldwide are HPV16 and HPV18 [1,2]. Although HPV DNA testing has been extensively studied for primary cervical cancer screening [3,4], this testing is currently not yet widely used. HPV infection is common, but more than 90% of HPV infections are transient and can be cleared in 1-2 years [5].
Source: Journal of Clinical Virology - Category: Virology Authors: Source Type: research