Structural role of Osteocalcin and Osteopontin in Energy Dissipation in Bone

This study used bone tissue from genetic deficient mice lacking OC and/or OPN and subjected them to a series of creep-fatigue-creep tests. To this end, whole tibiae were loaded in four-point bending to 70% stiffness loss which captured the three characteristic phases of fatigue associated with initiation, propagation, and coalescence of microdamage.

Source: Journal of Biomechanics - August 28, 2018 Category: Biomedical Science Authors: Ond řej Nikel, Atharva A. Poundarik, Stacyann Bailey, Deepak Vashishth Source Type: research