In vitro Activation of heme oxygenase-2 by menadione and its analogs

Conclusions These observations are consistent with the idea that naphthoquinones such as menadione bind to a receptor in HO-2 and activate the enzyme through a mechanism that may involve redox properties.

http://link.springer.com/10.1186/2045-9912-4-4

Source: Medical Gas Research - February 18, 2014 Category: Biomedical Science Source Type: research