An experimental protocol for in vivo imaging of neuronal structural plasticity with 2-photon microscopy in mice

Conclusions Repeated imaging of dendritic spines in vivo allows monitoring of long-term structural dynamics of synapses. When carefully controlled for influence of repeated anesthesia and phototoxicity, the method will be suitable to study changes in synaptic structural plasticity after brain injury.

http://link.springer.com/10.1186/2040-7378-5-9

Source: Experimental and Translational Stroke Medicine - July 10, 2013 Category: Neurology Source Type: research