Vitamin K2 supplementation blocks the beneficial effects of IFN- α-2b administered on the early stages of liver cancer development in rats

Hepatocellular carcinoma (HCC) is one of the most common malignancies worldwide with an estimated incidence of more than one million new cases per year [1]. Many cancer patients combine some forms of complementary and alternative medicine therapies with their conventional therapies. The most common choice of these treatments is the nutritional administration of certain essential compounds such as vitamins [2, 3]. In these connection, vitamin K is a fat-soluble essential vitamin; its only known physiological role is as a cofactor for γ-glutamyl-carboxylase, which acts on several blood-clotting proteins [4].

Source: Nutrition - August 25, 2018 Category: Nutrition Authors: Marina C. Vera, Florencia Lorenzetti, Alvaro Lucci, Carla G. Comanzo, Mar ía P. Ceballos, Gerardo B. Pisani, María de L. Alvarez, Ariel D. Quiroga, María C. Carrillo Source Type: research