Activation Toll-Like Receptor7 (TLR7) Responsiveness Associated with Mitogen- Activated Protein Kinase (MAPK) Activation in HIOEC Cell Line of Oral Squamous Cell Carcinoma

Conclusion: TLR7 is functionally over-expressed in HIOEC cell line of oral squamous cell carcinoma and development of resistance to cisplatin in human oral squamous cell carcinoma might occur through the mechanism involving activation of TLR7 and its dependent signaling pathway.  Key Words  Toll-Like Receptor 7; Mitogen-Activated Protein Kinase; Squamous Cell Carcinoma;
Source: Journal of Dentistry, Shiraz University of Medical Sciences - Category: Dentistry Source Type: research