Energy Metabolism and Bone

For most of the last century of bone research, the skeleton has been studied as a repository for calcium and phosphate ions singularly responsive to hormones that regulate mineral ion homeostasis. Work in the past two decades has changed our view of the skeleton by demonstrating its hormonal connection with other organs of metabolic control. Prominent among the emerging connections are leptin and insulin/insulin-like growth factor pathways, which assume central roles in regulating growth and metabolism in higher organisms.
Source: Bone - Category: Orthopaedics Authors: Source Type: research