Inflammation in older subjects with early- and late-onset depression in the NESDO study: a cross-sectional and longitudinal case-only design

Depression in old age is common with a prevalence of approximately 15% (Power et al., 2016). Although the prevalence of depression appears to remain unchanged over age (World Health Organization, 2016; Luppa et al., 2012), it has been suggested that depression that begins early in life (early-onset) is etiologically different from depression beginning at higher ages (late-onset depression) (Brodaty et al., 2001). Exploring the etiological differences between early-onset and late-onset depression is clinically relevant, given the potential implications for depression treatment at higher ages.

Source: Psychoneuroendocrinology - August 23, 2018 Category: Psychiatry Authors: M.P. Rozing, R. Veerhuis, R.G.J. Westendorp, P. Eikelenboom, M. Stek, R.M. Marijnissen, R.C. Oude Voshaar, H.C. Comijs, E. van Exel Source Type: research