Maintenance low dose systemic glucocorticoids have limited impact on bone strength and mineral density among incident renal allograft recipients: A pilot prospective cohort study

Soon after kidney transplant (KT), a decrease in parathormone and bone mineral density (BMD) occur, but little is known on the impact of KT on novel bone quality parameters including trabecular bone score (TBS) and bone material strength index (BMSi). We aimed to study BMD, TBS and BMSi in the first year after KT, in patients not treated with any bone therapy. A cohort including 36 patients underwent KT on a low-glucocorticoid-dose protocol (5  mg daily-prednisone from post-operative-day 42 onwards) and was observed for 12 months prospectively.

Source: Bone - August 23, 2018 Category: Orthopaedics Authors: Mar ía José Pérez-Sáez, Sabina Herrera, Daniel Prieto-Alhambra, Laia Vilaplana, Xavier Nogués, María Vera, Dolores Redondo-Pachón, Marisa Mir, Roberto Güerri, Marta Crespo, Adolfo Díez-Pérez, Julio Pascual Tags: Rapid Communication Source Type: research