Disc degeneration promotes regional inhomogeneity in the trabecular morphology of loaded rat tail vertebrae

ConclusionDisc degeneration promotes regional inhomogeneity in the vertebral trabecular morphology, with the convex region of the vertebrae having the worse trabecular bone morphology than the concave region.The translational potential of this article:Our study indicates that disc degeneration promotes regional inhomogeneity in the vertebral trabecular morphology. Regional variations in trabecular microarchitecture are helpful to predict vertebral fragility. This may help to elucidate the mechanisms by which disc degeneration contributes to vertebral fracture.
Source: Journal of Orthopaedic Translation - Category: Orthopaedics Source Type: research