Nuclear factor of activated T cells 5 maintained by Hotair suppression of miR-568 upregulates S100 calcium binding protein A4 to promote breast cancer metastasis
Conclusion:
This study unravels a detailed role of NFAT5 in mediating metastatic signaling, and provides broad insights into the involvement of Hotair, in particular, by transcriptionally regulating the expression of microRNA(s), in the metastasis of breast cancers.
Source: Breast Cancer Research - Category: Cancer & Oncology Authors: Jun-Tang LiLi-Feng WangYa-Li ZhaoTao YangWei LiJing ZhaoFeng YuLei WangYan-Ling MengNing-Ning LiuXiao-Shan ZhuChun-Fang GaoLin-Tao JiaAn-Gang Yang Source Type: research
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