Cutibacterium acnes protects Candida albicans from micafungin effect in biofilms

Candida albicans is an opportunistic pathogenic yeast, a commensal organism of the oral cavity, gastrointestinal and genito-urinary tracts and skin [1]. Immunocompromised patients can develop superficial candidiasis (oropharyngeal, vaginal, etc.) and candidemia [2]. In the United States of America (USA), Candida spp. is the fourth leading cause of nosocomial bloodstream infections (BSI) and 50.7 % of these infections are attributed to C. albicans [3]. In fact, many of these nosocomial BSI could involve more than one species of Candida and/or bacteria and half of them could be linked to implanted medical devices (IMD) [4,5].

Source: International Journal of Antimicrobial Agents - August 22, 2018 Category: Drugs & Pharmacology Authors: Cl ément Bernard, Noémie Renaudeau, Marie-Laure Mollichella, Nathalie Quellard, Marion Girardot, Christine Imbert Source Type: research