Evolution of HIV-1 transmitted drug resistance in Italy in the 2007 –2014 period: A weighted analysis

Transmitted drug resistance (TDR) represents a major concern for the efficacy of combined antiretroviral therapy (cART) [1], even showing a stable or even decreasing trend in Europe before 2010 [2,3]. This evidence may be explained at least in part by the stable and marked decrease observed in the frequency of acquired resistance, which has been observed in several clinical settings over the last decade [4 –6]. HIV-1 infected populations with different epidemiological characteristics, mainly related to the route of infection and the country of origin may be disproportionally affected by TDR [7–9].

Source: Journal of Clinical Virology - July 26, 2018 Category: Virology Authors: M. Franzetti, A. De Luca, F. Ceccherini-Silberstein, V. Spagnuolo, E. Nicastri, C. Mussini, A. Antinori, L. Monno, J. Vecchiet, I. Fanti, A. d ’Arminio Monforte, C. Balotta, on behalf of the ICONA Foundation Study Group Tags: Short communication Source Type: research