Lymph node yield as a predictor of overall survival following inguinal lymphadenectomy for penile cancer
Penile cancer is rare in the United States (US) with an incidence of 0.58/100,000 [1]. The majority of cases are squamous cell carcinoma. Management of penile squamous cell carcinoma (pSCC) is based on local invasiveness of the tumor, tumor grade, and staging of regional (inguinal and pelvic) lymph nodes (LNs) [2]. Involvement of the regional LNs is an adverse pathological finding and has been demonstrated to influence cancer-specific survival (CSS) and overall survival (OS) [3]. Inguinal lymphadenectomy (ILND) is, therefore, an important part of the treatment algorithm for clinically node positive disease (cN+) [4].
Source: Urologic Oncology: Seminars and Original Investigations - Category: Urology & Nephrology Authors: Nachiketh Soodana-Prakash, Tulay Koru-Sengul, Feng Miao, Diana M. Lopategui, Luis F. Savio, Kevin J. Moore, Taylor A. Johnson, Mahmoud Alameddine, Marcelo Panizzutti Barboza, Dipen J. Parekh, Sanoj Punnen, Mark L. Gonzalgo, Chad R. Ritch Tags: Original article Source Type: research
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