Is there an epidemic of chronic lymphocytic leukaemia (CLL) in China?

Chronic lymphocytic leukaemia (CLL) is common in Western countries with an incidence of 5-6/10E  + 5 population/year whereas the estimated incidence in Asia (including China) is 10- to 20-fold less1–4. The reason(s) for this discordance is unknown but seems predominately genetic. Studies of large cohorts of Chinese with CLL are rare and there are no population-based studies in mainland C hina. Several seeming differences between CLL in Chinese and persons of predominately European descent are reported such as younger age at diagnosis, atypical morphology, different immune phenotype and genotype and an increased proportion of IGHV mutated cases1.
Source: Leukemia Research - Category: Hematology Authors: Tags: Research paper Source Type: research