Affective modulation of target detection in deficit and non-deficit schizophrenia

Emotional deficits are an integral feature of schizophrenia (SZ), but our understanding of these deficits is limited. In the present study, we examined whether the severity of emotional deficits reflects difficulty in the cognitive processing of affectively valenced stimuli. Healthy controls (HC; N  = 170) and stable outpatients with SZ (N = 245), characterized as either deficit syndrome (DS; N = 62) or non-deficit syndrome (NDS; N = 183), completed an Affective Go/NoGo task requiring discrimination of positively, negatively or neutrally valenced words.

Source: Schizophrenia Research - August 17, 2018 Category: Psychiatry Authors: Pamela DeRosse, Chaya B. Gopin, Anita D. Barber, Anil K. Malhotra Source Type: research