Application of synthetic biology for production of chemicals in yeast Saccharomyces cerevisiae

We describe computational tools for the prediction of biochemical pathways, molecular biology methods for assembly of DNA parts into pathways, and for introducing the pathways into the host, and finally approaches for optimizing performance of the introduced pathways. Synthetic biology and metabolic engineering enable generation of novel cell factories that efficiently convert renewable feedstocks into biofuels, bulk and fine chemicals, thus creating the basis for biosustainable economy independent on fossil resources. This review describes synthetic biology applications for design, assembly and optimization of non‐native biochemical pathways in yeast S. cerevisiae.
Source: FEMS Yeast Research - Category: Research Authors: Tags: MiniReview Source Type: research