Clinical analysis of second primary gingival squamous cell carcinoma after radiotherapy

Oral cancer has become the sixth most common cancer in the world [1]. In 2015, approximately 45,780 new cases of cancer in the oral cavity and pharynx were reported in the United States. Of these, 8650 died due to cancer-related death [2]. Tobacco abuse and alcohol abuse have been identified as the most important risk factors for oral cancers, especially squamous cell carcinoma [3], as well as DNA oncogenic viruses and habits, such as chewing betel nut [4]. Among those patients with oral squamous cell carcinoma, a fraction was observed to have a history of radiotherapy in head and neck region.

Source: Oral Oncology - July 2, 2018 Category: Cancer & Oncology Authors: Xiaoyan Fu, Shuwei Chen, Weichao Chen, Zhongyuan Yang, Ming Song, Hao Li, Huayong Zhang, Fan Yao, Xuan Su, Tianrun Liu, An-Kui Yang Source Type: research