Neurocognitive performance predicts treatment outcome with cognitive behavioral therapy for major depressive disorder

Cognitive behavioral therapy (CBT) has been established as an effective treatment for depression (Luty et  al., 2007; Thase et al., 2007). However, CBT for Major Depressive Disorder (MDD) yields remission in only a minority of patients, with remission rates ranging from 20-50% (Cascalenda et al., 2002; DeRubeis et al., 2005; Driessen et al., 2013; Elkin et al., 1989). Identifying robust predictors of outcome with CBT for MDD could improve effective matching of patients to this treatment. CBT aims to correct maladaptive thinking which in turn decreases distress and depressive symptoms (DeRubeis et al., 2008).

Source: Psychiatry Research - August 13, 2018 Category: Psychiatry Authors: Allison V. Metts, John G. Keilp, Ronit Kishon, Maria A. Oquendo, J. John Mann, Jeffrey M. Miller Source Type: research